Secondly, only by keeping this option open can you function with true independence as a graduate student. If you perceive graduate school as your only option, you will be psychologically labile, inclined to get a bit desperate and insecure, and you will not be able to give your best.

Thirdly, if things really are not working out for you, then you are only hurting yourself and denying resources to others by staying in graduate school. There are a lot of interesting things to do in life besides being a scientist, and in some the job market is a lot better. If science is not turning you on, perhaps you should try something else. However, do not go off half-cocked. This is a serious decision. Be sure to talk to fellow graduate students and sympathetic faculty before making up your mind.

Avoid Taking Lectures - They're Usually Inefficient.

If you already have a good background in your field, then minimize the number of additional courses you take. This recommendation may seem counterintuitive, but it has a sound basis. Right now, you need to learn how to think for yourself. This requires active engagement, not passive listening and regurgitation.

To learn to think, you need two things: large blocks of time, and as much one-on-one interaction as you can get with someone who thinks more clearly than you do.

Courses just get in the way, and if you are well motivated, then reading and discussion is much more efficient and broadening than lectures. It is often a good idea to get together with a few colleagues, organize a seminar on a subject of interest, and invite a few faculty to take part. They'll probably be delighted. After all, it will be interesting for them, they'll love your initiative - and it will give them credit for teaching a course for which they don't have to do any work. How can you lose?

These comments of course do not apply to courses that teach specific skills: e.g., electron microscopy, histological technique, scuba diving.

Write a Proposal and Get It Criticized.

A research proposal serves many functions.

1. By summarizing your year's thinking and reading, it ensures that you have gotten something out of it.

2. It makes it possible for you to defend your independence by providing a concrete demonstration that you used your time well.

3. It literally makes it possible for others to help you. What you have in mind is too complex to be communicated verbally - too subtle, and in too many parts. It must be put down in a well-organized, clearly and concisely written document that can be circulated to a few good minds. Only with a proposal before them can they give you constructive criticism.